A Case Western Reserve University-led, Four-country Collaboration Identifies a Vaccine Target Against Plasmodium Vivax Malaria
Researchers at the Case Western Reserve University School of Medicine's Center for Global Health & Diseases have published novel findings indicating new antibodies inhibit infection by the Plasmodium vivax (P. vivax) malaria parasite.
The research by Brian T. Grimberg, Peter A. Zimmerman and Christopher L. King, which appears in the December issue of Public Library of Science Medicine (PLoS Medicine), offers one of the first feasible vaccine concepts for the most common form of malaria.
According to the researchers, unlike other types of malaria, a P. vivax infection relies solely upon the single molecular interaction between the Duffy antigen on human red blood cells and the Duffy binding protein expressed by the parasite to establish the disease. By interrupting this required interaction of parasite binding to red cell, the researchers and their colleagues around the United States and in Papua New Guinea, India and Thailand, offer a clear path toward development of a P. vivax malaria vaccine. Read more.
Case Western Reserve's Matt Paglia Named Third Team All-American
Case Western Reserve University junior forward/midfielder Matt Paglia has been named a third team All-American by the National Soccer Coaches Association of America (NSCAA). The announcement was made on the NSCAA Web site.
Paglia, who was a first-team NSCAA Great Lakes All-Region honoree, scored a team best eight goals for the No. 22 ranked Spartans (12-5-1) this season and had one assist. He was a first team All-University Athletic Association (UAA) selection as he finished sixth in the UAA in goals.
"Matt has worked very hard the last three years to be a better athlete and a better player," said head coach Dan Palmer."He spent extra time refining his game and has become a very efficient and very dangerous forward."
In 2006, Paglia scored nine goals and handed out nine assists as Case Western Reserve won its first UAA title and made its first appearance in the NCAA postseason. The Spartans made it to the "Sweet 16" and finished the season ranked No. 12. He posted two goals and two assists in 2005, his rookie year. Read more.
Calling hours for Littleton "L.T." Organ, who died December 13, will be from 9 a.m. to 9 p.m. December 21 at the William A. Gaines Funeral Home, 9116 Union Ave. in Cleveland. Organ was a biographical maintenance and gift processor in the office of Advancement Services, and was part of the university community for 17 years. Funeral services will begin at 9:30 a.m., December 22 at the Allen Chapel Missionary Baptist Church, 9333 Miles Ave. in Cleveland.
Access Services will close at 2 p.m., December 20. The office will reopen at 8:30 a.m., December 21.
To get the latest weather conditions, along with the campus forecast, go to the Case Weather Station Web site.
For Faculty & Staff
The Manor House at Squire Valleevue Farm can be rented for private events as well as for university business.
The Manor House at Squire Valleevue Farm is located in Hunting Valley, Ohio, about 10 miles east of the main university campus. Find out more details by viewing the Manor House Web page.
This section will be updated occasionally during the winter break. Refer to the "Campus News" section for general information.