Medical School Faculty Member Suggests New Model for Development of Schizophrenia

Robert Findling, M.D.

Doctors have long known schizophrenia has a genetic basis, and have hypothesized that the disease resulted from combinations of common genes, or alleles, each contributing towards the disease in a small way. But a new study co-authored by a Case Western Reserve University School of Medicine faculty member suggests that a predisposition to schizophrenia may instead be caused by just a few, rare genetic mutations, each contributing significantly to the disease.

The study, "Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia," has been published in the April 2008 issue of Science magazine. It was co-authored by Robert Findling, the Rocco L. Motto, M.D. Professor of Child and Adolescent Psychiatry at the School of Medicine, and director of Child and Adolescent Psychiatry at Case Medical Center, a partnership between the School of Medicine and University Hospitals. Read more.

Student Athletes Earn Honors at Case Western Reserve's Sports Banquet

Spartan Mascot

Case Western Reserve University's Department of Physical Education and Athletics recently handed out its annual awards at the 2008 All-Sports Banquet.

Ten students representing various sports earned accolades. Read more for a description of each award and the winners.

University's Engaging the Campus Summit to Feature Collaborative Technologies

One of the many highlights of Case Western Reserve University's Collaborative Technology and Community Engagement Summit May 8 will be the OneCommunity launch of the new and expanded University Circle wireless mesh network.

The free event from 9 a.m. to 4 p.m., May 8 in Thwing Center also will feature a keynote address, "Mass Collaboration and the Future of Higher Education," by Anthony Williams, the co-author of Wikinomics. Case Western Reserve President Barbara R. Snyder will be offering remarks following the keynote.

The program also offers more than 16 breakout sessions and 40 speakers and demonstrations, including a panel session featuring Cory Ondrejka, founder of Second Life, on "Collaboration Technology -- What's Next: Bold Predictions, Cautionary Notes and Take Away Lessons."

A local nonprofit operator of one of the world's largest fiber-optic broadband networks, OneCommunity officially will unveil its free public outdoor wireless mesh network to start off the summit. The network will cover a five-square-mile area throughout University Circle, parts of East Cleveland, Cleveland Heights and Cleveland.

Details on programming and registration for the summit are available online.

Those unable to attend in person can participate through SecondLife after creating an avatar. In addition, much of the programming will be offered online in new near-high definition streaming (H264).

Campus News

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Kelvin Smith Library invites the campus community to take its 24x7 Service Survey. The three-question, online survey will help the library's staff gauge areas of importance regarding 24-hour access to the facility.

Researchers at Case Western Reserve University are conducting a study on appetite and food preoccupation in order to understand what areas of the brain are involved in eating and food motivation. Overweight, healthy volunteers are needed to help the researchers understand normal brain processes in response to viewing food cues. Children and adults ages 12 to 35 are invited to participate. Lunch will be provided, and individuals will be compensated for participation in a four-hour study. For information, contact Brian Fishman at 368-0112.

For Faculty and Staff

May 1 is the deadline to apply for the Staff Advisory Council's Staff Educational Enhancement Fund for summer 2008. Funds can be used for textbooks, online courses, certification, training sessions, conferences, conventions, professional association meetings, and workshops that are not funded under regular university benefits. Funds may not be used for travel-related expenses (food, transportation, lodging, etc.). Send application to Kathleen Dowdell or Kathleen O' Linn.

For Students

All seniors who recently received an e-mail invitation from Interim Provost Jerold S. Goldberg to participate in the College Senior Survey are asked to complete the evaluation as soon as possible. This Web-based survey questions seniors about their undergraduate experience on campus. Responses will help university leadership understand and improve student life and learning. For details, e-mail Thomas Geaghan.

The Graduate Student Senate is sponsoring a Spring Barbecue for all graduate students from 4:30 to 8 p.m., May 8 at Freiberger Field. There will be free food and beverages. In addition, campus groups and departments such as the sustainability program and the School of Graduate Studies will have information tables at the event.

Applications are being accepted for graduate student research grants, sponsored by the Baker-Nord Center for the Humanities. Grants up to a maximum amount of $500 are available to graduate students in the humanities and related disciplines for research expenses not covered by departmental support. The deadline is October 24. For the application and guidelines, go online or call 368-8961.

Events

The Law-Medicine Center Symposium presents "Newborn Screening for Nontreatable Disorders," featuring several well-renowned guest speakers, from 1-4:30 p.m., May 2 at the Whitehall Room, Renaissance Hotel, downtown Cleveland. Free, open to the public. Co-sponsored by the Inamori International Center for Ethics and Excellence and the Center for Genetic Research, Ethics and Law.

Clarification: The Center for Science and Mathematics Education's "Science is Fun! Family Day" begins at 10 a.m., May 3 in Nord Hall, Room 310. Volunteers are still needed, and they are asked to report at 9 a.m. The free event will include science activities, friendly competitions and demonstrations throughout the day. To RSVP for attendance or to volunteer, call 368-5075, or send e-mail to Kathryn Kwiatkowski.

The views and opinions of those invited to speak on campus do not necessarily reflect the views of the university administration or any other segment of the university community.

April 30, 2008

A daily newsletter published by the Office of Marketing & Communications, Case Western Reserve University. Submit items for inclusion to: case-daily@case.edu.

Case in the News

A class blog studies fair use

Chronicle of Higher Education, April 29, 2008
Peter B. Friedman, an associate professor of law at Case Western Reserve University, has created a blog for students to hash out a debate about a fictional copyright-infringement case.

Human lab rats loan bodies to science for cash

MSNBC.com, April 27, 2008
Every year, millions of Americans loan their bodies to science. Some are desperate to find a cure for what ails them. Others who are healthy just participate in the occasional study for some extra cash. Nick Pesa, a fourth-year medical student at Case Western Reserve University, takes a more low-tech approach to finding trials. He and fellow classmates Nikolai Sopko and Jason Snyder scour the newspapers and bulletin boards at Case Western Reserve, University Hospitals, and the Cleveland Clinic.

Lifelong running calls for knowing when to stop, if only temporarily

The Plain Dealer, April 29, 2008
Distance running is a sport with enormous mental and physical benefits, but experts estimate as many as 70 percent of runners have an injury every year. Shana Miskovsky, an orthopedic and foot and ankle surgeon at Case Medical Center, a partnership between Case Western Reserve University School of Medicine and University Hospitals, comments.

Higher Ed News

Fuzzier, more intimate online controversy

Inside Higher Ed, April 30, 2008
Those wishing to go to confession can find comfort, anonymity and a sympathetic ear on the Internet. Many, many sympathetic ears — and perhaps a few mean-spirited ones, too. Students and administrators are gradually confronting that reality with the latest batch of anonymous message boards to crop up at colleges.

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