Case Western Reserve Grants Option to Startup Thermalin Diabetes Inc.
for Insulin Analog Therapies

Case Western Reserve University has granted an 18-month, exclusive option to startup Thermalin Diabetes Inc. regarding a portfolio of insulin analogs. The company must reach certain milestones in order to exercise its option to obtain an exclusive license on therapies designed to help patients with diabetes.

Cleveland-based Thermalin Diabetes is developing treatments that it hopes will become an important part of the $12 billion, rapidly growing insulin market. Insulin is a therapeutic protein used to manage blood sugar levels. Innovations in the 1990s led to the introduction of insulin analogs with superior therapeutic performance.

"This is one of the coolest technologies that we've seen, because of the potential to serve mankind," said Joseph Jankowski, Case Western Reserve's associate vice president for technology management within the university's Technology Transfer Office.

Potential for improved treatment of Type 1 and Type 2 diabetes results from the work of Michael Weiss, chair of the Department of Biochemistry at Case Western Reserve University's School of Medicine. His approximately 20 years of research into the structure and function of biological molecules has focused on insulin, insulin analogs and insulin receptors. Read more.

Campus News

President Barbara R. Snyder and Provost William A. "Bud" Baeslack cordially invite the Case Western Reserve University community to a reception welcoming Rick Bischoff, vice president for enrollment; David Fleshler, associate provost for international affairs; and Donald Stewart, vice president for financial planning. The reception will take place from 3:30 to 5 p.m., Friday, Jan. 8, in the Hovorka Atrium.

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SAGES Café is now serving Peet's Holiday Blend Coffee, Special Holiday Blend Black Tea and Eggnog. The campus community is invited to stop by and indulge in classic and new holiday treats.


To get the latest weather conditions, along with the campus forecast, visit the Case Weather Station Web site.

For Faculty and Staff

The German Marshall Fund of the United States (GMF) announces a call for applications for fellowships being offered through its Comparative Domestic Policy program (CDP), jointly supported by the Compagnia di San Paolo and Bank of America. The fellowships are intended to commence between May and October 2010, ending no later than March 2011. Fellows will be awarded a grant of $10,000 per month to support a fellowship lasting approximately two to six months on the other side of the Atlantic, during which time fellows will research approaches to an urban/regional challenge confronted by both American and European cities and regions. Applications are due March 15, 2010. Up to four fellowships will be awarded. Learn more.

For Students

Students are invited to check out Church of the Covenant's Cache Resale Shop for last minute holiday shopping needs. The shop is open from 10 a.m. to 4 p.m. on Tuesday, Dec. 15, and Thursday, Dec. 17. There are many items available for less than $1.

Events

The next Science Café Cleveland, sponsored by the university's Sigma Xi chapter, will focus on the topic of "Deafness and Imbalance: Advances in Treatments and Understanding Using Zebrafish." The speakers are Brian McDermott, otolaryngology, Case Western Reserve, and Cliff Megerian, director of otology and neurotology, University Hospitals. The talk begins at 7 p.m. tonight at the Great Lakes Brewing Company's Tasting Room, 2701 Carroll Ave.

The Clinical and Translational Science Collaborative (CTSC) invites the campus community to attend its seminar series presentation at 4:30 p.m., Tuesday, Dec. 15, in Frohring Auditorium (105 Biomedical Research Building). The featured speakers are Michael Kattan, chair of Quantitative Health Sciences at the Cleveland Clinic, and J. Sunil Rao, professor in the Department of Epidemiology and Biostatistics at Case Western Reserve. They will discuss the progress being made in the Translational Methodologies Working Group.

The views and opinions of those invited to speak on campus do not necessarily reflect the views of the university administration or any other segment of the university community.

Et al.

The Diabetes Association of Greater Cleveland's Dietrich Diabetes Research Institute (DDRI) recently presented its 2009 Lifetime Achievement in Diabetes Research Award to two Cleveland-area physicians renowned for their research in the area of diabetes: Vincent M. Monnier of Case Western Reserve University School of Medicine, and Patrick M. Catalano of MetroHealth Medical Center. They were honored at the 6th Annual DDRI/CWRU Diabetes Research Symposium last month. The DDRI Lifetime Achievement in Diabetes Research Award recognizes select scientists, researchers or physicians who have significantly contributed toward improving the quality of life for those living with diabetes. Monnier, a professor in the Department of Pathology, conducts research on the structure and significance of protein changes by advanced Maillard reaction (reducing sugars) and oxidation products in aging and age-related diseases, including diabetes, cataract and end-stage renal disease. Catalano is a professor of reproductive biology at Case Western Reserve and serves as chair of the Department of Reproductive Biology at the university and at MetroHealth Medical Center. He served as chair of the DDRI Task Force from 2003-2008.

December 14, 2009

A daily newsletter published by the Office of Marketing & Communications, Case Western Reserve University. Submit items for inclusion to: case-daily@case.edu.

Case in the News

Case Western Reserve University grants option to startup Thermalin Diabetes

The Medical News, Dec. 14, 2009
Case Western Reserve University has granted an 18-month, exclusive option to startup Thermalin Diabetes Inc. regarding a portfolio of insulin analogs. The company must reach certain milestones in order to exercise its option to obtain an exclusive license on therapies designed to help patients with diabetes.

Study shows link between working memory and reactive parenting

NewsLeader.com, Dec. 14, 2009
Any parent knows that sometimes maintaining your cool with misbehaving children can be a challenge. We all have times when we get frustrated or angry and lash out at someone without thinking. A new study by psychologists at Virginia Tech and two other universities suggests that parents with poorer working memory skills are less likely to be able to control their emotions with their children. Case Western Reserve University is involved with the research.

Just getting started

Crain's Cleveland Business, Dec. 14, 2009
When VasoLux MicroSystems LLC moved into the Great Lakes Innovation and Development Enterprise on the campus of Lorain County Community College in Elyria it was little more than an idea — an idea that needed time to grow, time to incubate. Now, nearly five years later, its fiber-optic, minimally invasive probe, which measures the extent of damage in joints' cartilage, is ready for U.S. Food and Drug Administration trials. The article on incubators references Scott Shane, A. Malachi Mixon III Professor of Entrepreneurial Studies at Case Western Reserve University.

New OSU center to focus on obese kids

Columbus Dispatch, Dec. 14, 2009
The U.S. Centers for Disease Control and Prevention are adding Ohio State University to a network of researchers studying ways to prevent disease. Case Western Reserve University also was approved to start a prevention research center. The two schools have discussed ways to collaborate on research.

Reconnecting the brain

Forbes.com, Dec. 28, 2009
Researchers are working to reconstruct the nervous system so that paralyzed limbs might be active again. The brains of the patients Hunter Peckham and John Donoghue are trying to help fire off instructions by the millions, every second of the day. The messages, little packets of electrical information, are intended for the far reaches of the patients' bodies, where perfectly capable muscles await word. But none of the messages gets through; the muscles lie dormant. Injuries, strokes or disease have severed the connection between brain and body. Peckham is a professor of biomedical engineering at Case Western Reserve University.

Twins offer football team a winning spirit times two

WKYC.com, Dec. 14, 2009
Every Case Western Reserve University football practice begins the same way, with two men taking the field to lead the team in a special brand of jumping jacks called "Spartan Jacks." The men aren't players or coaches, but twin brothers, Ronald and Donald Cunningham, from the neighborhood surrounding the university.

Higher Ed News

Defaults nearly double

Inside Higher Ed, Dec. 14, 2009
Scores more colleges could face federal restrictions on financial aid once the government starts holding them accountable for their three-year student loan cohort default rates, judging from the first look at three-year rates made public by the U.S. Education Department today. Taken together, the three-year rates are 93 percent higher than the standard two-year rates for for-profit colleges, 63 percent higher for public two-year institutions, and 70 percent higher for private four-year colleges.